Molecular Modeling and Drug Design
  • About us
  • Research
  • Publications
  • Members
  • Webservers
  • Calendar
  • Blog
  • Benchmarks
  • ALLODD
  • Image Gallery
  • Publicity
  • Talks
Picture
Picture
Picture
Picture
Picture
Picture
Picture
Picture
The inside cover picture shows the optimization of a small-molecule inhibitor of Arp2/3 complex, a seven-subunit 225 kD protein that nucleates branched actin filaments. The X-ray structure of the complex bound to a known inhibitor, CK-666, was solved, and computational, synthetic, and biochemical methods were used to generate a novel inhibitor with improved potency—an important tool compound for dissecting the cellular functions of Arp2/3 complex. For more details, see the Full Paper by Baggett, Cournia et al. on p. 1286 ff.
Picture
Evi performs cell-based in vitro assays
Picture
The Biomedical Research Foundation of the Academy of Athens
Picture
Picture

Picture
Powered by Create your own unique website with customizable templates.