|Molecular Modeling and Drug Design||
In the body, a compound’s electron-rich aniline group tends to change into a highly reactive quinone that can bind to nontarget proteins. Novartis’ first-generation inhibitor of the enzyme anaplastic lymphoma kinase (TAE684, left) had such an aniline group formed potentially harmful protein adducts in the body. To reduce side effects, chemists moved the position of the troublesome nitrogen to make the current version of the drug. For more information see:
rsync is a utility software and network protocol for Unix-like systems (with ports to Windows) that synchronizes files and directories from one location to another while minimizing data transfer by using delta encoding when appropriate.
You can also transfer files by rsync in the background, e.g.
rsync -e 'ssh -x' -avxSDHP email@example.com:/data/cournia .
type in the password, the transfer starts
Alexis, Dora, Vassilis, Dimitris, Anastasia, Petros, Manuela, Zoe
lab group members!
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